VThunter: a database for single-cell screening of virus target cells in the animal kingdom.

ABSTRACT: Viral infectious diseases are a devastating and continuing threat to human and animal health. Receptor binding is the key step for viral entry into host cells. Therefore, recognizing viral receptors is fundamental for understanding the potential tissue tropism or host range of these pathogens. The rapid advancement of single-cell RNA sequencing (scRNA-seq) technology has paved the way for studying the expression of viral receptors in different tissues of animal species at single-cell resolution, resulting in huge scRNA-seq datasets. However, effectively integrating or sharing these datasets among the research community is challenging, especially for laboratory scientists. In this study, we manually curated up-to-date datasets generated in animal scRNA-seq studies, analyzed them using a uni

SUBMITTER: Chen D 

PROVIDER: S-EPMC8728219 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature