Ontology highlight
ABSTRACT:
SUBMITTER: Ben Guebila M
PROVIDER: S-EPMC8728257 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Ben Guebila Marouen M Lopes-Ramos Camila M CM Weighill Deborah D Sonawane Abhijeet Rajendra AR Burkholz Rebekka R Shamsaei Behrouz B Platig John J Glass Kimberly K Kuijjer Marieke L ML Quackenbush John J
Nucleic acids research 20220101 D1
Gene regulation plays a fundamental role in shaping tissue identity, function, and response to perturbation. Regulatory processes are controlled by complex networks of interacting elements, including transcription factors, miRNAs and their target genes. The structure of these networks helps to determine phenotypes and can ultimately influence the development of disease or response to therapy. We developed GRAND (https://grand.networkmedicine.org) as a database for computationally-inferred, conte ...[more]