Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study.

ABSTRACT:

Objectives

The steroid hormone vitamin D has roles in immunomodulation and bone health. Insufficiency is associated with susceptibility to respiratory infections. We report 25-hydroxy vitamin D (25(OH)D) measurements in hospitalised people with COVID-19 and influenza A and in survivors of critical illness to test the hypotheses that vitamin D insufficiency scales with illness severity and persists in survivors.

Design

Cross-sectional study.

Setting and participants

Plasma was obtained from 295 hospitalised people with COVID-19 (International Severe Acute Respiratory and emerging Infections Consortium (ISARIC)/WHO Clinical Characterization Protocol for Severe Emerging Infections UK study), 93 with influenza A (Mechanisms of Severe Acute Influenza Consortium (MOSAIC) st

SUBMITTER: Hurst EA 

PROVIDER: S-EPMC8728359 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature