Association between hormone replacement therapy and carpal tunnel syndrome: a nationwide population-based study.

ABSTRACT:

Objective

Carpal tunnel syndrome (CTS) is the most common compressive focal mononeuropathy, and the increased incidence in postmenopausal and pregnant women suggests its association with oestrogen. The objective of this study is to evaluate the relationship between hormone replacement therapy (HRT) and the occurrence of CTS.

Design

Population-based case-control study.

Setting

Nationwide health insurance programme operated by the government with a near 100% coverage rate.

Participants

We identified women ≥45 years old in the Health Insurance Research Database of Taiwan, which contains data on a representative sample of one million enrollees. After exclusion of those who were diagnosed with CTS before the prescription of HRT, a total of 118 309 participants were

SUBMITTER: Tang HC 

PROVIDER: S-EPMC8728457 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature