Association Between Maternal Hormonal Contraception Use and Central Nervous System Tumors in Children.

ABSTRACT:

Importance

The incidence of central nervous system (CNS) tumors in children appears to be increasing, yet few risk factors are established. There is limited information regarding whether maternal hormonal contraception use increases this risk.

Objective

To examine the association between maternal hormonal contraception use and CNS tumors in children (<20 years).

Design, setting, and participants

In this nationwide cohort study based on population-based registry data, 1 185 063 children born in Denmark between January 1, 1996, and December 31, 2014, were followed up for a diagnosis of a CNS tumor (final follow-up on December 31, 2018).

Exposures

Maternal hormonal contraception use was analyzed according to any use, regimen (combined/progestin only), and route of

SUBMITTER: Hargreave M 

PROVIDER: S-EPMC8728605 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature