Infection in Patients with Suspected Thrombotic Microangiopathy Based on Clinical Presentation.

ABSTRACT:

Background and objectives

In contrast to shigatoxin-associated Escherichia coli (STEC) causing hemolytic uremic syndrome, STEC-unrelated infections associated with thrombotic microangiopathy are less characterized.

Design, setting, participants, & measurements

Our retrospective study in a four-hospital institution of 530 consecutive patients with adjudicated thrombotic microangiopathies during the 2009-2016 period studied STEC-unrelated infections' epidemiology and major outcomes (death, acute dialysis, and major cardiovascular events).

Results

STEC-unrelated infection was present in 145 of 530 (27%) patients, thrombotic microangiopathies without infection were present in 350 of 530 (66%) patients, and STEC causing hemolytic and uremic syndrome was present in 3

SUBMITTER: Thoreau B 

PROVIDER: S-EPMC8729578 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature