Carbon-Based Fiber Materials as Implantable Depth Neural Electrodes.

ABSTRACT: Implantable brain electrophysiology electrodes are valuable tools in both fundamental and applied neuroscience due to their ability to record neural activity with high spatiotemporal resolution from shallow and deep brain regions. Their use has been hindered, however, by the challenges in achieving chronically stable operations. Furthermore, implantable depth neural electrodes can only carry out limited data sampling within predefined anatomical regions, making it challenging to perform large-area brain mapping. Minimizing inflammatory responses and associated gliosis formation, and improving the durability and stability of the electrode insulation layers are critical to achieve long-term stable neural recording and stimulation. Combining electrophysiological measurements with simultaneous

SUBMITTER: Fu X 

PROVIDER: S-EPMC8730365 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature