Exercise Training and Cognitive Function in Kidney Disease: Protocol for a Pilot Randomized Controlled Trial.

ABSTRACT:

Background

Chronic kidney disease (CKD) is extremely common in older adults and is associated with cognitive impairment. It is hypothesized that accelerated cognitive decline in CKD results from a vascular dysfunction-induced reduction in the integrity of the brain white matter.

Objective

The aim of this study was to describe the protocol for a study to evaluate whether exercise training provides a cerebroprotective effect by improving cerebrovascular health.

Methods

This is a randomized controlled trial investigating feasibility and effect size.

Results

Participants will be randomized to either a 24-week, home-based, walking program or a usual care group. Participants will undergo evaluation of cognitive function, brain structure via magnetic reasoning imaging

SUBMITTER: Bronas UG 

PROVIDER: S-EPMC8732305 | biostudies-literature | 2022 Jan-Feb 01

REPOSITORIES: biostudies-literature