A randomized controlled trial of a structured program combining aerobic and resistance exercise for adults with type 2 diabetes in Japan.

ABSTRACT:

Background

We assessed the effect of supervised, combined aerobic and resistance exercise on diabetic parameters in Japanese patients with type 2 diabetes mellitus (T2DM).

Methods

This 12-week, multicenter (17 medical institutions), open-label, parallel-group study (clinicaltrials.jp; JapicCTI-184002), randomized (1:1) Japanese patients aged 20-75 years with T2DM and hemoglobin A1c (HbA1c) of 7.0-10.0% to supervised exercise (n = 113) or standard therapy (n = 115). The supervised exercise group undertook supervised aerobic (30 min) and resistance exercise 3 times/week (20 designated gyms). Primary endpoint was change in HbA1c from baseline at week 13. Secondary endpoints were change in fasting blood glucose (FBG), glycoalbumin, fasting insulin, homeostatic mode

SUBMITTER: Terauchi Y 

PROVIDER: S-EPMC8733075 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature