Chinese herbal medicine for myasthenia gravis: A systematic review and meta-analysis of randomized clinical trials.

ABSTRACT:

Background

Myasthenia Gravis (MG) is a disorder of neuromuscular transmission bringing mild ocular weakness to severe generalized muscle weakness and disability. The conventional treatments have long-term side effects, and Chinese herbal medicines (CHM) have shown possible effect and safety for MG patients, but the existing evidence was not robust enough and the results were out of date.

Methods

Searching for randomized controlled trials (RCTs) was conducted in 7 databases and clinical trial registries until July 2021. The ROB 2 tool was used to assess the study quality and GRADE was used to assess the quality of whole evidence. Meta-analyses were conducted and the results were presented as risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI).

Results

SUBMITTER: Zhu SJ 

PROVIDER: S-EPMC8733270 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature