Prospective Study of Serum Uric Acid Levels and First Stroke Events in Chinese Adults With Hypertension.

ABSTRACT: Objectives: We investigated the association between serum uric acid (SUA) levels and the risk of the first stroke in Chinese adults with hypertension. Methods: A total of 11, 841 hypertensive patients were selected from the Chinese Hypertension Registry for analysis. The relationship between SUA levels and first stroke was determined using multivariable Cox proportional hazards regression, smoothing curve fitting, and Kaplan-Meier survival curve analysis. Results: During a median follow-up of 614 days, 99 cases of the first stroke were occurred. Cox proportional hazards models indicated that SUA levels were not significantly associated with the first stroke event [adjusted-hazard ratio (HR) per SD increase: 0.98, 95% CI 0.76-1.26, P = 0.889]. In comparison to th

SUBMITTER: Hu F 

PROVIDER: S-EPMC8733595 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature