The C. elegans mapping locus rol-9 is encoded by a gain-of-function mutation in mlt-11.
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ABSTRACT:
SUBMITTER: Rich MS
PROVIDER: S-EPMC8733821 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
The <i>C. elegans</i> mapping locus <i>rol-9</i> is encoded by a gain-of-function mutation in <i>mlt-11</i>.
Rich Matthew S MS Nix Paola P Jorgensen Erik M EM
microPublication biology 20220105
We mapped <i>rol-9</i> to the <i>mlt-11</i> locus (encoded by the gene W01F3.3) on the far-right end of chromosome V. The canonical allele of <i>rol-9</i>, <i>sc148</i>, is an in-frame deletion in a conserved exon of the protein that creates a gain-of-function roller phenotype. <i>sc148</i> deletes a short peptide of unknown function conserved in nematodes. ...[more]
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