Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders.

ABSTRACT:

Importance

Although the association between several recurrent genomic copy number variants (CNVs) and mental disorders has been studied for more than a decade, unbiased, population-based estimates of the prevalence, disease risks and trajectories, fertility, and mortality to contrast chromosomal abnormalities and advance precision health care are lacking.

Objective

To generate unbiased, population-based estimates of prevalence, disease risks and trajectories, fertility, and mortality of CNVs implicated in neuropsychiatric disorders.

Design, setting, and participants

In a population-based case-cohort study, using the Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) 2012 database, individuals born between May 1, 1981, and December 31, 2005, a

SUBMITTER: Calle Sanchez X 

PROVIDER: S-EPMC8733851 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature