Clinical Characteristics, Disease Course, and Outcomes of Patients With Acute Generalized Exanthematous Pustulosis in the US.

ABSTRACT:

Importance

Acute generalized exanthematous pustulosis (AGEP) is a rare, severe cutaneous adverse reaction associated with systemic complications. Currently available data are largely limited to small retrospective case series.

Objective

To describe the clinical characteristics, disease course, and outcomes of a heterogeneous group of patients with AGEP across the US.

Design, setting, and participants

A retrospective review of a case series of patients was conducted from January 1, 2000, through July 31, 2020. All 340 included cases throughout 10 academic health systems in the US were scored retrospectively using the EuroSCAR scoring system, and patients with a score corresponding to probable or definite AGEP and aged 18 years or older were included.

Main outcomes a

SUBMITTER: Creadore A 

PROVIDER: S-EPMC8733866 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature