OncoSNIPE® Study Protocol, a study of molecular profiles associated with development of resistance in solid cancer patients.

ABSTRACT:

Background

Nowadays, evaluation of the efficacy and the duration of treatment, in context of monitoring patients with solid tumors, is based on the RECIST methodology. With these criteria, resistance and/or insensitivity are defined as tumor non-response which does not allow a good understanding of the diversity of the underlying mechanisms. The main objective of the OncoSNIPE® collaborative clinical research program is to identify early and late markers of resistance to treatment.

Methods

Multicentric, interventional study with the primary objective to identify early and / or late markers of resistance to treatment, in 600 adult patients with locally advanced or metastatic triple negative or Luminal B breast cancer, non-small-cell lung cancer or pancreatic ductal adenocarci

SUBMITTER: Vachenc S 

PROVIDER: S-EPMC8734369 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature