Diurnal RNAPII-tethered chromatin interactions are associated with rhythmic gene expression in rice.

ABSTRACT:

Background

The daily cycling of plant physiological processes is speculated to arise from the coordinated rhythms of gene expression. However, the dynamics of diurnal 3D genome architecture and their potential functions underlying the rhythmic gene expression remain unclear.

Results

Here, we reveal the genome-wide rhythmic occupancy of RNA polymerase II (RNAPII), which precedes mRNA accumulation by approximately 2 h. Rhythmic RNAPII binding dynamically correlates with RNAPII-mediated chromatin architecture remodeling at the genomic level of chromatin interactions, spatial clusters, and chromatin connectivity maps, which are associated with the circadian rhythm of gene expression. Rhythmically expressed genes within the same peak phases of expression are preferentially tether

SUBMITTER: Deng L 

PROVIDER: S-EPMC8734370 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature