Mean platelet volume and mean platelet volume to platelet count ratio as predictors of severity and mortality in sepsis.

ABSTRACT:

Introduction

Sepsis is a public health problem due to its high prevalence and mortality. Mean platelet volume (MPV), a biomarker reported in routine blood counts, has been investigated and shows promise for determining fatal outcomes in septic patients.

Objective

Evaluate whether the mean platelet volume (MPV) and mean platelet volume-to-platelet count (MPV/P) ratio are predictors of clinical severity and mortality in patients with sepsis.

Methods

A prospective population cohort of 163 patients aged 18-97 years was recruited at the Intensive Care Unit of Pablo Arturo Hospital, Quito, Ecuador from 2017-2019 and followed up for 28 days. Patients were diagnosed with sepsis based on SEPSIS-3 septic shock criteria; in which the MPV and the MPV/P ratio were measured on days

SUBMITTER: Velez-Paez JL 

PROVIDER: S-EPMC8735631 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature