Association of the VEGFR2 single nucleotide polymorphism rs2305948 with glioma risk.

ABSTRACT:

Background

Many studies have reported a relationship between the vascular endothelial growth factor receptor 2 single nucleotide polymorphism (SNP) rs2305948 and glioma, but their conclusions have been controversial. A meta-analysis was performed to assess the association between rs2305948 and glioma susceptibility.

Methods

Inclusion criteria and a strategy for screening of original literature were created. Eligible articles on the correlation between the SNP rs2305948 and glioma were identified in the PubMed, Embase, Web of Science, Cochrane Library, CNKI and Wanfang databases. After extracting the data, Stata 12. 0 software was used to perform statistical analysis under 5 genetic models and to calculate the combined odds ratio (OR) value and its 95% confidence interval (CI

SUBMITTER: Sun S 

PROVIDER: S-EPMC8735747 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature