Efficient Syntheses of Biobased Terephthalic Acid, p-Toluic Acid, and p-Methylacetophenone via One-Pot Catalytic Aerobic Oxidation of Monoterpene Derived Bio-p-cymene.

ABSTRACT: An efficient elevated-pressure catalytic oxidative process (2.5 mol % Co(NO₃)₂, 2.5 mol % MnBr₂, air (30 bar), 125 °C, acetic acid, 6 h) has been developed to oxidize p-cymene into crystalline white terephthalic acid (TA) in ∼70% yield. Use of this mixed Co²⁺/Mn²⁺ catalytic system is key to obtaining high 70% yields of TA at relatively low reaction temperatures (125 °C) in short reaction times (6 h), which is likely to be due to the synergistic action of bromine and nitrate radicals in the oxidative process. Recycling studies have demonstrated that the mixed metal catalysts present in recovered mother liquors could be recycled three times in successive p-cymene oxidation reactions with no loss in catalytic activity or TA

SUBMITTER: Tibbetts JD 

PROVIDER: S-EPMC8735764 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature