Surgical management and oncological outcome of non-squamous cell carcinoma of the larynx: a bicentric study.

ABSTRACT:

Purpose

Non-squamous cell carcinoma (non-SCC) accounts for about 5% of laryngeal malignancies. Survival data are limited, and consensus on management principles is lacking. The present study reviews our experience in the surgical treatment of non-metastatic non-SCC of the larynx and compares oncological and functional outcomes in a cohort of patients affected by traditional SCC.

Methods

We collected data on 592 patients affected by laryngeal neoplasms. Univariate and multivariable survival analyses were performed using Cox proportional-hazards models; survival estimates were reported by hazard ratios (HR) with 95% confidence intervals (CI), and survival curves were established with the Kaplan-Meier method.

Results

We identified 326 patients affected by untreated SCC,

SUBMITTER: Iandelli A 

PROVIDER: S-EPMC8738708 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature