Real-world data in elderly men from Yokosuka City 15 years after introducing prostate-specific antigen-based population screening.

ABSTRACT: Mass screening based on prostate-specific antigen (PSA) reduces mortality in prostate cancer. However, the effectiveness of this screening in the elderly has not been demonstrated. In the city of Yokosuka, Japan, PSA screening has been conducted since 2001 and the present study examined the real-world status of PSA-based population screening in the elderly. It retrospectively evaluated 1,117 prostate cancer patients >75 years of age. The patients were divided into two groups: The screened group comprising patients diagnosed by PSA-based population screening or workplace screening and PSA follow-up patients at urology clinics; and the non-screened group comprising patients detected by other methods. Overall survival (OS), cancer-specific survival (CSS) and factors contributing to shorter CS

SUBMITTER: Nirei T 

PROVIDER: S-EPMC8739438 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature