COVID-19 related outcomes among individuals with neurodegenerative diseases: a cohort analysis in the UK biobank.

ABSTRACT:

Background

An increased susceptibility to COVID-19 has been suggested for individuals with neurodegenerative diseases, but data are scarce from longitudinal studies.

Methods

In this community-based cohort study, we included 96,275 participants of the UK Biobank who had available SARS-CoV-2 test results in Public Health England. Of these, 2617 had a clinical diagnosis of neurodegenerative diseases in the UK Biobank inpatient hospital data before the outbreak of COVID-19 (defined as January 31st, 2020), while the remaining participants constituted the reference group. We then followed both groups from January 31st, 2020 to June 14th, 2021 for ascertainment of COVID-19 outcomes, including any COVID-19, inpatient care for COVID-19, and COVID-19 related death. Logistic regression

SUBMITTER: Hu Y 

PROVIDER: S-EPMC8739517 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature