Collective behavior of magnetic microrobots through immuno-sandwich assay: On-the-fly COVID-19 sensing.

ABSTRACT: Mobile self-propelled micro/nanorobots are mobile binding surface that improved the sensitivity of many biosensing system by "on-the-fly" identification and isolation of different biotargets. Proteins are powerful tools to predict infectious disease progression such as COVID-19. The main methodology used to COVID-19 detection is based on ELISA test by antibodies detection assays targeting SARS-CoV-2 virus spike protein and nucleocapside protein that represent an indirect SARS-CoV-2 detection with low sentitivy and specificity. Moreover ELISA test are limited to used external shaker to obtain homogenously immobilization of antibodies and protein on sensing platform. Here, we present magnetic microrobots that collective self-assembly through immuno-sandwich assay and they can be used as mobi

SUBMITTER: Mayorga-Martinez CC 

PROVIDER: S-EPMC8739527 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature