Diagnostic accuracy of calprotectin in periprosthetic joint infection: a diagnostic meta-analysis.

ABSTRACT:

Background

Periprosthetic joint infection (PJI) is considered to be one of the most challenging complications of joint replacement, which remains unpredictable. As a simple and emerging biomarker, calprotectin (CLP) has been considered to be useful in ruling out PJI in recent years. The purpose of this study was to investigate the accuracy and sensitivity of CLP in the diagnosis of PJI.

Methods

We searched and screened the publications from PubMed, Web of Science, EMBASE, and Cochrane Library from database establishment to June 2021. Subsequently, Stata version 16.0 software was used to combine the pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), operating characteristic curve, and area under the

SUBMITTER: Xing J 

PROVIDER: S-EPMC8739654 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature