Cortical Stimulation Paired With Volitional Unimanual Movement Affects Interhemispheric Communication.

ABSTRACT: Cortical stimulation (CS) of the motor cortex can cause excitability changes in both hemispheres, showing potential to be a technique for clinical rehabilitation of motor function. However, previous studies that have investigated the effects of delivering CS during movement typically focus on a single hemisphere. On the other hand, studies exploring interhemispheric interactions typically deliver CS at rest. We sought to bridge these two approaches by documenting the consequences of delivering CS to a single motor cortex during different phases of contralateral and ipsilateral limb movement, and simultaneously assessing changes in interactions within and between the hemispheres via local field potential (LFP) recordings. Three macaques were trained in a unimanual reaction time (RT)

SUBMITTER: Yun R 

PROVIDER: S-EPMC8739774 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature