The Diagnostic Accuracy Of Procalcitonin for Urinary Tract Infection in Hospitalized Older Adults: a Prospective Study.

ABSTRACT:

Background

The diagnosis of urinary tract infection (UTI) is challenging among hospitalized older adults, particularly among those with altered mental status.

Objective

To determine the diagnostic accuracy of procalcitonin (PCT) for UTI in hospitalized older adults.

Design

We performed a prospective cohort study of older adults (≥65 years old) admitted to a single hospital with evidence of pyuria on urinalysis. PCT was tested on initial blood samples. The reference standard was a clinical definition that included the presence of a positive urine culture and any symptom or sign of infection referable to the genitourinary tract. We also surveyed the treating physicians for their clinical judgment and performed expert adjudication of cases for the determination of UTI.

SUBMITTER: Choi JJ 

PROVIDER: S-EPMC8741546 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature