Pseudomonas aeruginosa rhamnolipid micelles deliver toxic metabolites and antibiotics into Staphylococcus aureus.
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ABSTRACT:
SUBMITTER: Gdaniec BG
PROVIDER: S-EPMC8741607 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
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<i>Pseudomonas aeruginosa</i> rhamnolipid micelles deliver toxic metabolites and antibiotics into <i>Staphylococcus aureus</i>.
Gdaniec Bartosz Gerard BG Bonini Fabien F Prodon François F Braschler Thomas T Köhler Thilo T van Delden Christian C
iScience 20211220 1
Efficient delivery of toxic compounds to bacterial competitors is essential during interspecies microbial warfare. Rhamnolipids (RLPs) are glycolipids produced by <i>Pseudomonas</i> and <i>Burkholderia</i> species involved in solubilization and uptake of environmental aliphatic hydrocarbons and perform as biosurfactants for swarming motility. Here, we show that RLPs produced by <i>Pseudomonas aeruginosa</i> associate to form micelles. Using high-resolution microscopy, we found that RLP micelles ...[more]
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