Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions.

ABSTRACT:

Aims/hypothesis

Sleep, diet and exercise are fundamental to metabolic homeostasis. In this secondary analysis of a repeated measures, nutritional intervention study, we tested whether an individual's sleep quality, duration and timing impact glycaemic response to a breakfast meal the following morning.

Methods

Healthy adults' data (N = 953 [41% twins]) were analysed from the PREDICT dietary intervention trial. Participants consumed isoenergetic standardised meals over 2 weeks in the clinic and at home. Actigraphy was used to assess sleep variables (duration, efficiency, timing) and continuous glucose monitors were used to measure glycaemic variation (>8000 meals).

Results

Sleep variables were significantly associated with postprandial glycaemic control (2 h incrementa

SUBMITTER: Tsereteli N 

PROVIDER: S-EPMC8741723 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature