Comparison of cytotoxicity effects induced by four different types of nanoparticles in human corneal and conjunctival epithelial cells.

ABSTRACT: The impact of particulate matter (PM) on ocular surface health has attracted increased attention in recent years. Previous studies have reported that differences in the chemical composition of PM can affect the toxicological response. However, available information on the toxic effects of chemical components of PM on the ocular surface is insufficient. In this paper, we aimed to investigate the toxicity effects of chemical components of PM on the ocular surface, focusing on the effects of four different types of nanoparticles (NPs) in human corneal epithelial cells (HCECs) and human conjunctival epithelial cells (HCjECs), which include titanium dioxide (TiO₂), carbon black (CB), zinc dioxide (ZnO), and silicon dioxide (SiO₂). We found that the in vitro cytotoxic effec

SUBMITTER: Li X 

PROVIDER: S-EPMC8742118 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature