Antiherpetic drugs: a potential way to prevent Alzheimer's disease?

ABSTRACT:

Background

Considering the growing body of evidence suggesting a potential implication of herpesviruses in the development of dementia, several authors have questioned a protective effect of antiherpetic drugs (AHDs) which may represent a new means of prevention, well tolerated and easily accessible. Subsequently, several epidemiological studies have shown a reduction in the risk of dementia in subjects treated with AHDs, but the biological plausibility of this association and the impact of potential methodological biases need to be discussed in more depth.

Methods

Using a French medico-administrative database, we assessed the association between the intake of systemic AHDs and the incidence of (i) dementia, (ii) Alzheimer's disease (AD), and (iii) vascular dementia in 68,29

SUBMITTER: Linard M 

PROVIDER: S-EPMC8742322 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature