A Preliminary Study of Different Treatment Strategies for Anxious Depression.

ABSTRACT:

Background

Despite the best treatments, about 20% of patients with major depressive disorder (MDD) receiving drugs and psychological intervention show little or no improvement. There is no trial comparing different treatment methods in patients with anxiety/somatic subtype MDD.

Aim

To compare the efficacy and safety of various treatments in patients with anxiety/somatic subtype MDD.

Methods

This was a preliminary multicenter randomized controlled trial at eight participating hospitals in China (09/2016-06/2019) (ClinicalTrials.gov #NCT03219008). The patients were randomized to mirtazapine/SNRIs, mirtazapine/SNRIs+cognitive behavioral therapy (CBT), mirtazapine+SNRIs, or mirtazapine+SNRIs+physical therapies (modified electroconvulsive treatment or repetitive transcrani

SUBMITTER: Wang Y 

PROVIDER: S-EPMC8742615 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature