An early relook identifies high-risk trajectories in ambulatory advanced heart failure.

ABSTRACT:

Introduction

Patients with ambulatory advanced heart failure (HF) are increasingly considered for durable mechanical circulatory support (MCS) and heart transplantation and their effective triage requires careful assessment of the clinical trajectory.

Methods

REVIVAL, a prospective, observational study, enrolled 400 ambulatory advanced HF patients from 21 MCS/transplant centers in 2015-2016. Study design included a clinical re-assessment of Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) profile within 120 days after enrollment. The prognostic impact of a worsening INTERMACS Profile assigned by the treating physician was assessed at 1 year after the Early Relook.

Results

Early Relook was done in 325 of 400 patients (81%), of whom 24% had

SUBMITTER: Kittleson MM 

PROVIDER: S-EPMC8742755 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature