Changing epidemiology of hand, foot, and mouth disease in China, 2013-2019: a population-based study.

ABSTRACT:

Background

Hand, foot, and mouth disease (HFMD) is an important public health problem. A monovalent EV-A71 vaccine was launched in China in 2016. Previous studies showed that inactivated monovalent EV-A71 vaccines were highly efficient against HFMD associated with EV-A71 but not against HFMD with other etiologies, leading to a hypothesis that the introduction of EV-A71 vaccines might change the pathogen spectrum and epidemiological trend of HFMD. In this study, we described for the first time the changing epidemiological characteristics of HFMD after the launch of the EV-A71 vaccine.

Methods

We extracted individual-based epidemiological data on HFMD cases reported to the Chinese Center for Disease Control and Prevention between January 2013 and December 2019. We described th

SUBMITTER: Hong J 

PROVIDER: S-EPMC8743221 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature