Penicillinase plasmid Australia type in Neisseria gonorrhoeae isolated in Poland.

ABSTRACT:

Purpose

Neisseria gonorrhoeae is an etiological agent of gonorrhea which remains a major public health problem the mechanisms that determine resistance to drugs of the beta-lactam class, which are recommended for the treatment of gonorrhea, are currently the most important problem in its treatment. Chromosomal mutations are responsible for resistance to ceftriaxone and cefepime. The possibility of mutations in the gene encoding beta-lactamase (bla_TEM) in the penicillinase plasmid may also turn out to be a serious threat.

Methods

The occurrence of resistance encoded on penicillinase plasmid has been investigated. For this purpose, the susceptibility of bacteria was determined and the gene for resistance to beta-lactams as well as the plasmids themselves was typed.<

SUBMITTER: Walter de Walthoffen S 

PROVIDER: S-EPMC8743264 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature