Acute and early developmental outcomes of children with Duarte galactosemia.

ABSTRACT: A recent study demonstrated that children with Duarte galactosemia (DG) do not show increased prevalence of detectable developmental complications when 6-12 years old. However, that study left unanswered whether infants with DG might be at increased risk for acute problems when drinking milk or whether children with DG younger than 6 years might show increased prevalence of perhaps transient developmental challenges. Here, we have addressed both of these questions by analyzing parent/guardian-reported data collected retrospectively for 350 children, 206 with DG and 144 unaffected siblings from the same families. The variables analyzed included whether each child had experienced (1) acute complications in infancy, (2) early intervention services when <3 years old, and/or (3) special educati

SUBMITTER: Fridovich-Keil JL 

PROVIDER: S-EPMC8743335 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature