Concurrence and impact of hepatic steatosis on chronic hepatitis B patients: a systematic review and meta-analysis.

ABSTRACT:

Background

The association between hepatic steatosis (HS) and chronic hepatitis B (CHB) remains controversial. We performed a systematic review and meta-analysis to investigate the latest concurrence rate and impact of HS on CHB patients.

Methods

Relevant studies were identified by searching PubMed, EMBASE, and the Cochrane Library from January 1, 2000 to December 2, 2020. We calculated the pooled prevalence of HS in CHB patients using a random effects model. A subgroup analysis was performed to explore the impact of HS on CHB patients. This study is registered with PROSPERO (No. CRD42021242584).

Results

A total of 98 studies with a population of 48,472 patients were included. The global prevalence of HS in CHB patients was 34.93% [95% confidence interval (CI): 32.01-

SUBMITTER: Jiang D 

PROVIDER: S-EPMC8743703 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature