In vivo reflectance confocal microscopy of wounds: feasibility of intraoperative basal cell carcinoma margin assessment.

ABSTRACT:

Background

In vivo reflectance confocal microscopy (RCM) is well established in non-melanoma skin cancer detection and screening. However, there is no sufficient validation regarding intraoperatively obtained images of wound margins. A reliable and fast resection margin detection is of high clinical relevance. Hence, we aimed to investigate feasibility and validity of in vivo RCM imaging for wound margins assessment compared with standard skin surface imaging and the gold standard histopathology.

Methods

A surgical incision through the center of a large basal cell carcinoma (BCC) affected area in the head and face region was performed. After removing half of the tumor, the wound margins of the remaining half as well as the corresponding skin surface were scanne

SUBMITTER: Shavlokhova V 

PROVIDER: S-EPMC8743714 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature