Serum Sodium, Patient Symptoms, and Clinical Outcomes in Hospitalized Patients with COVID-19.

ABSTRACT:

Introduction

Disorders of serum sodium (SNa) are common in hospitalized patients with COVID-19 and may reflect underlying disease severity. However, the association of SNa with patient-reported outcomes is not clear.

Methods

The Brigham and Women's Hospital COVID-19 Registry is a prospective cohort study of consecutively admitted adult patients with confirmed SARS-CoV-2 infection (n = 809). We examined the associations of SNa (continuous and tertiles) on admission with: (1) patient symptoms obtained from detailed chart review; and (2) in-hospital mortality, length of stay, and intensive care unit (ICU) admission using unadjusted and adjusted logistic regression models. Covariates included demographic data and comorbidities.

Results

Mean age was 60 years, 48% were male

SUBMITTER: Yen TE 

PROVIDER: S-EPMC8744185 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature