Ontology highlight
ABSTRACT:
SUBMITTER: Poh L
PROVIDER: S-EPMC8744307 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Poh Luting L Sim Wei Liang WL Jo Dong-Gyu DG Dinh Quynh Nhu QN Drummond Grant R GR Sobey Christopher G CG Chen Christopher Li-Hsian CL Lai Mitchell K P MKP Fann David Y DY Arumugam Thiruma V TV
Molecular neurodegeneration 20220109 1
There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical role in disease onset and progression. However, there is a limited understanding of the underlying pathophysiology of VCI, especially in relation to CCH. Neuroinflammation is a significant contributor in the progression of VCI as increased systemic levels of the proinflammatory cytokine interleukin-1β (IL-1β) has been ex ...[more]