Impact of time to intubation on mortality and pulmonary sequelae in critically ill patients with COVID-19: a prospective cohort study.

ABSTRACT:

Question

We evaluated whether the time between first respiratory support and intubation of patients receiving invasive mechanical ventilation (IMV) due to COVID-19 was associated with mortality or pulmonary sequelae.

Materials and methods

Prospective cohort of critical COVID-19 patients on IMV. Patients were classified as early intubation if they were intubated within the first 48 h from the first respiratory support or delayed intubation if they were intubated later. Surviving patients were evaluated after hospital discharge.

Results

We included 205 patients (140 with early IMV and 65 with delayed IMV). The median [p₂₅;p₇₅] age was 63 [56.0; 70.0] years, and 74.1% were male. The survival analysis showed a significant increase in the risk of mort

SUBMITTER: Gonzalez J 

PROVIDER: S-EPMC8744383 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature