Hyperglycemia on Admission Predicts Acute Kidney Failure and Renal Functional Recovery among Inpatients.

ABSTRACT: Hyperglycemia is associated with adverse outcomes in hospitalized patients. We aimed to assess the impact of glucose levels upon admission on the subsequent deterioration or improvement of kidney function in inpatients with a focus on diabetes or reduced baseline kidney function as possible modifiers of this effect. Running a retrospective cohort analysis, we compared patients with normal vs. high glucose levels upon admission. We applied multivariable logistic regression models to study the association between baseline glucose levels with subsequent renal and clinical outcomes. Interaction terms were used to study a possible modifier effect of diabetes. Among 95,556 inpatients (52% males, mean age 61 years), 15,675 (16.5%) had plasma glucose higher than 180 mg/dL, and 72% of them were dia

SUBMITTER: Gorelik Y 

PROVIDER: S-EPMC8745405 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature