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The Role of Vitamin D Supplementation in Children with Autism Spectrum Disorder: A Narrative Review.


ABSTRACT: Children with autism spectrum disorder (ASD) present with persistent deficits in both social communication and interactions, along with the presence of restricted and repetitive behaviors, resulting in significant impairment in significant areas of functioning. Children with ASD consistently reported significantly lower vitamin D levels than typically developing children. Moreover, vitamin D deficiency was found to be strongly correlated with ASD severity. Theoretically, vitamin D can affect neurodevelopment in children with ASD through its anti-inflammatory properties, stimulating the production of neurotrophins, decreasing the risk of seizures, and regulating glutathione and serotonin levels. A Title/Abstract specific search for publications on Vitamin D supplementation trials up to June

SUBMITTER: Kittana M 

PROVIDER: S-EPMC8746934 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature