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Complexes of Glucarolactones with Water-Soluble Copolymers of N-Vinylpyrrolidone with N-Vinylamine as Inhibitors of β-Glucuronidase Efficacy.

ABSTRACT: Water-soluble complexes of N-vinylpyrrolidone/N-vinylamine copolymers with lactones of D-glucuronic acid were obtained and characterized by chromatographic, spectral, and hydrodynamic methods. The complexes efficiently inhibited the enzyme β-glucuronidase that causes the appearance of bladder tumors. The products demonstrated prolonged action and were stable during storage.

SUBMITTER: Krasikov VD

PROVIDER: S-EPMC8747385 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Complexes of Glucarolactones with Water-Soluble Copolymers of N-Vinylpyrrolidone with N-Vinylamine as Inhibitors of β-Glucuronidase Efficacy.

Krasikov Valerii D VD Santuryan Yulia G YG Malahova Irina I II Ivanov Alexey G AG Gorshkov Nikolay I NI Panarin Evgenii F EF

Polymers 20211228 1

Water-soluble complexes of N-vinylpyrrolidone/N-vinylamine copolymers with lactones of D-glucuronic acid were obtained and characterized by chromatographic, spectral, and hydrodynamic methods. The complexes efficiently inhibited the enzyme β-glucuronidase that causes the appearance of bladder tumors. The products demonstrated prolonged action and were stable during storage. ...[more]

PMID: 35012128

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