Bioallethrin activates specific olfactory sensory neurons and elicits spatial repellency in Aedes aegypti.

ABSTRACT:

Background

Use of pyrethroid insecticides is a pivotal strategy for mosquito control globally. Commonly known for their insecticidal activity by acting on voltage-gated sodium channels, pyrethroids, such as bioallethrin and transfluthrin, are used in mosquito coils, emanators and other vaporizers to repel mosquitoes and other biting arthropods. However, whether specific olfactory receptor neurons are activated by pyrethroids to trigger spatial repellency remains unknown.

Results

We used behavioral and electrophysiological approaches to elucidate the mechanism of bioallethrin repellency in Aedes aegypti, a major vector of dengue, yellow fever, Zika and chikungunya viruses. We found that bioallethrin elicits spatial (i.e. non-contact) repellency and activates a specific type o

SUBMITTER: Valbon W 

PROVIDER: S-EPMC8748403 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature