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Dataset on the effects of environmentally relevant humic acid concentrations on the liver protein profile in Japanese medaka (Oryzias latipes).

ABSTRACT: The data were obtained by a label-free quantification approach from a shotgun proteomics experiment, using STrap sample processing technique for protein digestion and high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) for peptide analysis. MaxQuant data processing was used to obtain proteomics data. The dataset reflects changes in the liver protein profile of Japanese medaka exposed to 0, 5, 40 and 80 mg/L nominal concentrations of Sigma-Aldrich humic acid for 96 h. Actual concentrations of humic acid were measured using the potassium dichromate photometric method and reported in mg organic carbon/L. These proteomics data are relevant for further insights into fish stress responses to humic substances-related challenge.

SUBMITTER: Yurchenko VV

PROVIDER: S-EPMC8749161 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Dataset on the effects of environmentally relevant humic acid concentrations on the liver protein profile in Japanese medaka (<i>Oryzias latipes</i>).

Yurchenko Victoria V VV Morozov Alexey A AA Fedorov Roman A RA Bakina Ludmila G LG Zgoda Victor G VG Tikhonova Olga V OV

Data in brief 20220105

The data were obtained by a label-free quantification approach from a shotgun proteomics experiment, using STrap sample processing technique for protein digestion and high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) for peptide analysis. MaxQuant data processing was used to obtain proteomics data. The dataset reflects changes in the liver protein profile of Japanese medaka exposed to 0, 5, 40 and 80 mg/L nominal concentrations of Sigma-Aldrich humic acid for 96 h ...[more]

PMID: 35036493

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