Risk of Developing Melanoma With Systemic Agents Used to Treat Psoriasis: A Review of the Literature.

ABSTRACT:

Background

Psoriasis is a chronic inflammatory skin disease induced by autoimmune-like dysregulation of the immune system. Treatment options have drastically evolved in recent years, and treatment advances that target specific cytokines and other molecules involved in dysregulation have had a profound effect in controlling the disease.

Objective

We reviewed the literature to assess the risk of developing melanoma with conventional therapies and newer agents used to treat psoriasis.

Methods

A comprehensive literature search using Medline (via Ovid) and Embase was conducted.

Results

The majority of studies reviewed reported insignificant results. Potential risk for melanoma was identified for only 3 out of 15 anti-psoriatic treatments analyzed: adalimumab (relati

SUBMITTER: Semaka A 

PROVIDER: S-EPMC8750137 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature