CT-based structural analyses of vertebral fractures with polymeric augmentation: A study of cadaveric three-level spine segments.

ABSTRACT: Pathologic vertebral fractures due to metastasis can occur under normal physiologic activities, leading to pain and neurologic deficit. Prophylactic vertebroplasty is a technique used to augment vertebral strength and reduce the risk of fracture. Currently, no technique is available to objectively assess vertebral fracture risk in metastatically-involved vertebral bodies. The aim of the current study was to develop an image-based computational technique to estimate fracture force outcomes during bending. To this end, mechanical testing was performed on intact, simulated defect, PMMA-augmented, and PPF-augmented 3-level spine segments from both sexes under a compression/flexion-type loading condition. The augmentation performance of poly(methyl methacrylate) (PMMA) and poly(propylene fumara

SUBMITTER: Rezaei A 

PROVIDER: S-EPMC8750312 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature