Ontology highlight
ABSTRACT:
SUBMITTER: Verta R
PROVIDER: S-EPMC8750506 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Verta Roberta R Grange Cristina C Skovronova Renata R Tanzi Adele A Peruzzi Licia L Deregibus Maria Chiara MC Camussi Giovanni G Bussolati Benedetta B
Cells 20220103 1
Extracellular vesicles (EVs) and viruses share common features: size, structure, biogenesis and uptake. In order to generate EVs expressing the SARS-CoV-2 spike protein on their surface (S-EVs), we collected EVs from SARS-CoV-2 spike expressing human embryonic kidney (HEK-293T) cells by stable transfection with a vector coding for the S1 and S2 subunits. S-EVs were characterized using nanoparticle tracking analysis, ExoView and super-resolution microscopy. We obtained a population of EVs of 50 t ...[more]