Burden of SARS-CoV-2 and protection from symptomatic second infection in children.

ABSTRACT:

Importance

The impact of the SARS-CoV-2 pandemic on children remains unclear. Better understanding of the burden of COVID-19 among children and their protection against re-infection is crucial as they will be among the last groups vaccinated.

Objective

To characterize the burden of COVID-19 and assess how protection from symptomatic re-infection among children may vary by age.

Design

A prospective, community-based pediatric cohort study conducted from March 1, 2020 through October 15, 2021.

Setting

The Nicaraguan Pediatric Influenza Cohort is a community-based cohort in District 2 of Managua, Nicaragua.

Participants

A total of 1964 children aged 0-14 years participated in the cohort. Non-immunocompromised children were enrolled by random selection from a

SUBMITTER: Kubale J 

PROVIDER: S-EPMC8750653 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature