Intrinsic Capacity Predicts Negative Health Outcomes in Older Adults.

ABSTRACT:

Background

Monitoring trajectories of intrinsic capacity (IC) in older adults has been suggested by the World Health Organization as a means to inform prevention to avoid or delay negative health outcomes. Due to a lack of longitudinal studies, it is currently unclear how IC changes over time and whether repeatedly measured IC predicts negative health outcomes.

Methods

Based on 4 751 repeated observations of IC (range = 0-100) during 21 years of follow-up among 754 older adults 70 and older, we assessed longitudinal trajectories of IC, and whether time-varying IC predicted the risk of chronic activities of daily living disability, long-term nursing home stay, and mortality using joint models.

Results

Average IC declined progressively from 77 to 11 points during follow

SUBMITTER: Stolz E 

PROVIDER: S-EPMC8751795 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature